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lytB [2019-02-22 16:04:03]
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lytB [2019-02-22 16:04:03]

modifier protein of major autolysin LytC
locus
BSU35630
pI
9.84
mw
76.55 kDa
protein length
705 aa Sequence Blast
gene length
2118 bp Sequence Blast
function
autolysis
product
modifier protein of major autolysin LytC
essential
no
synonyms
cwbA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,660,648 → 3,662,765

    The protein

    [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|497C9654DC7514FF738D18E1F083299C43003A4C|lytA]-[gene|E1F9922DF7273040F84E5AC207A9F4CAFB85DC75|lytB]-[gene|6A21293823151C6980BF52B31A4B249A8440F2E1|lytC]
    description
    [Pubmed|1357079]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1357079], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|1357079], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]

    • regulatory mechanism

  • [protein|5A6FBAE6553343092862CB79E150F934978C32A9|SinR]: repression, in [regulon|5A6FBAE6553343092862CB79E150F934978C32A9|SinR regulon]
  • [protein|7098319D8E88FDC2A629A3F4A21507FD7A649385|YvrHb]: repression, [Pubmed|16306698], in [regulon|7098319D8E88FDC2A629A3F4A21507FD7A649385|YvrHb regulon]
  • [protein|920F91E748EE079FF864011D9052B073567C41E4|SlrR]: repression, (in complex with [protein|5A6FBAE6553343092862CB79E150F934978C32A9|SinR]) [Pubmed|20351052], in [regulon|920F91E748EE079FF864011D9052B073567C41E4|SlrR regulon]
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    Biological materials

    Mutant

  • 1A789 ( ''lytB''::''kan''), [Pubmed|1588906], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A789&Search=1A789 BGSC]
  • BKE35630 (Δ[gene|E1F9922DF7273040F84E5AC207A9F4CAFB85DC75|lytB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAATTTCAGGTTCCTCCC, downstream forward: _UP4_TGATTATTTTAGGATATAAC
  • BKK35630 (Δ[gene|E1F9922DF7273040F84E5AC207A9F4CAFB85DC75|lytB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAATTTCAGGTTCCTCCC, downstream forward: _UP4_TGATTATTTTAGGATATAAC

    • References

  • 1355454,16306698,1357079,20351052,9158733